I tried Hyper-V, and of course, I had to install a virtual DragonFly system. Sascha Wildner very helpfully pointed out that DragonFly on Hyper-V requires a legacy network adapter and a gen-1 image type; both changes you can make during initial setup. I’m noting it here for the benefit of future people walking down the same path.
Note: pick ‘legacy BIOS’ during the actual DragonFly install, too.
How was the performance?
Installed quickly enough – I haven’t had a chance to install anything past that, really.